Advance to Healthier Gums and Stronger Teeth* with Crest Pro-Health Advanced. This toothpaste contains ActivClean Crystals for advanced stain prevention. Crest Pro-Health Advanced Bacteria Guard Mint Toothpaste cleans beyond what you can see and continues to work between brushings. It is made with patented stannous fluoride. It provides 8 advanced benefits in 1, including: protection against cavities, plaque and gingivitis, acid erosion and tooth sensitivity for whole mouth health